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« Médecines douces », « médecines naturelles », « médecines traditionnelles », « médecines complémentaires », « médecines intégratives », « médecines du mode de vie », « soins paramédicaux », « soins de support », etc. : il est temps de sortir de la nébuleuse.En une vingtaine d’années, des études ont permis d’isoler des méthodes efficaces et sûres, et de les distinguer des « médecines alternatives », des « médecines parallèles », des « fake medicines » et des « dérives sectaires ». Les scientifiques les appellent des interventions non médicamenteuses (INM). Elles ont pris place dans la prévention, le soin et les traitements au côté des traitements biomédicaux autorisés. Les professionnels disposent aujourd’hui d’INM mieux décrites, mieux validées, mieux ciblées, mieux dosées, mieux personnalisables, mieux associables et mieux suivies.Ce livre fait un état des lieux de ce secteur en pleine croissance mondiale. Il propose des clés pour en comprendre les enjeux à travers une analyse globale, transversale et scientifique. D’une lecture accessible, il permet à tout professionnel ou usager de situer chaque INM à sa juste place.

Therapeutics --- Complementary Therapies --- Therapeutic Uses --- Alternative medicine --- Thérapeutique non médicamenteuse --- Utilisations thérapeutiques. --- Thérapies complémentaires. --- Guides pratiques.

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Comprehensive Health Care --- Cardiovascular Agents --- Vascular Diseases --- Therapeutic Uses --- Cardiovascular Diseases --- Patient Care Management --- Pharmacologic Actions --- Diseases --- Health Services Administration --- Health Care --- Chemical Actions and Uses --- Chemicals and Drugs --- Primary Health Care --- Hypertension --- Antihypertensive Agents

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Hyperlipidemias --- Hypolipidemic Agents --- Dyslipidemias --- Antimetabolites --- Lipid Regulating Agents --- Therapeutic Uses --- Molecular Mechanisms of Pharmacological Action --- Lipid Metabolism Disorders --- Pharmacologic Actions --- Metabolic Diseases --- Chemical Actions and Uses --- Nutritional and Metabolic Diseases --- Chemicals and Drugs --- Diseases --- Anticholesteremic Agents --- Hypercholesterolemia

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Contraceptives, Oral --- Hormone Replacement Therapy --- Drug Therapy --- Contraceptive Agents, Female --- Therapeutics --- Contraceptive Agents --- Reproductive Control Agents --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Therapeutic Uses --- Physiological Effects of Drugs --- Pharmacologic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Contraceptives, Oral, Hormonal --- Estrogen Replacement Therapy --- Medicine --- Health & Biological Sciences --- Oncology --- Diagnostic Techniques and Procedures.

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There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. Road map to anticancer drug development from discovery to NDA submission Discussion of molecular targets and preclinical screening Development and validation of bioanalytical methods Chapters on clinical trial design and phase 0, I, II, III clinical trials Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents Review of the drug development process from both laboratory and clinical perspectives New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development.

Antineoplastic Agents -- pharmacokinetics. --- Antineoplastic Agents -- pharmacology. --- Antineoplastic agents -- Research -- Handbooks, manuals, etc. --- Antineoplastic agents. --- Antineoplastic agents --- Therapeutic Uses --- Pharmacologic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Antineoplastic Agents --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Research --- Anticancer agents --- Antineoplastic drugs --- Antineoplastics --- Antitumor agents --- Antitumor drugs --- Cytotoxic drugs --- Inhibitors, Neoplasm --- Neoplasm inhibitors --- Pharmacy. --- Chemistry --- Medicine --- Drugs --- Materia medica --- Pharmacology --- Cancer --- Chemotherapy